Work

Clinical significance and correlation of microRNA-21 expression in patients undergoing transcatheter aortic valve replacement

Year: 2025

Type: article

Abstract: A significant drop in circulating microRNA-21 levels 6 h after transcatheter aortic valve replacement (TAVR) was associated with a fourfold increased risk of major adverse cardiovascular or cerebrovascular events (MACCE). This prospective study identifies microRNA-21 as a promising early biomarker for risk stratification and prognosis after TAVR, offering potential for more personalized postprocedural care.

Source: American Journal of Physiology-Heart and Circulatory Physiology

DOI: 10.1152/ajpheart.00506.2025

Authors: Anat Berkovitch, Zvi Sirotkin, Yoni Grossman, Victor Guetta, Paul Fefer, Amit Segev, Elad Maor, Gidi Paret, Shlomi Matetzky, Yael Nevo-Caspi, Israel Moshe Barbash

Institutions: Tel Aviv University, Sheba Medical Center, Edmond and Lily Safra Children's Hospital

Language: English

Topic: Cardiac Valve Diseases and Treatments

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4413640981

FWCI:

Cites: 25

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Related to: 10