P78 | Usefulness of an ad hoc questionnaire (Acro-PREV) for the acromegaly diagnosis in general medical outpatient
Year: 2025
Type: conference-abstract
Abstract: Background and Aim: Acromegaly (ACRO) is characterized by increased release of growth hormone and, consequently, insulin-like growth factor I (IGF1), most often by a pituitary adenoma. The estimated prevalence is 40-125 cases/million but targeted universal screening studies have found a higher prevalence (about 10 fold). The aim of the present study was to investigate the usefulness of Acro-PREV questionaire to diagnosis ACRO between patients attending general medical outpatient.Methods: The Acro-PREV investigate the main symptoms, physical changes and comorbities of ACRO. A self-administered questionnaire was provided to patients attending general medical outpatient. IGFI was measured in patients with ≥1 acral symptom/ physical changes and ≥2 comorbidities.Results: Of the 200 patients enrolled, 54 patients (27%) were tested for IGF1, 1 case of ACRO were diagnosed. A male patient of 54 year old were diagnosed of acromegaly due to a pituitary macroadenoma GH-secreting.Conclusions: In conclusion ACRO-PREV could be an useful tool for ACRO diagnosis, however further studies are needed on larger populations.
Source: Italian Journal of Medicine
Authors: Vo Van Kha, Tran Thi Huong Ly, Pham Thi Thanh Hoa, Vo Huynh Nhu, Damas Hendriansyah, Nusratuddin Abdullah, Rudy B. Leonardy, Mardiah Tahir, Samrichard Rambulangi, Firdaus Hamid, Filomena Pietrantonio, Vera Kopsaj, Francesco Rosiello, Aurora Tomassoni, Luca Moriconi, Donatella Padua, Kiki Rizki Amelia, Efendi Lukas, Nurbani Bangsawan, Isharyah Sunarno, Retno Budiarti Farid, Sriwijaya Qadar, Rabab H. Elshaikh, Ashok Kumar Sah, Abdelrahman Mohamed Abukanna, Abdulrahman Algarni, Ammar Abdelmola, Hussam Ali Osman, Tagwa Yousif Elsayed Yousif, Elryah I. Ali, Hiba Ali, Ayman Hussein Alfeel, Thanh Long Nguyen, Victor Storm, Lam Toi Phung, Cong Thien Le, Thi Thu Ha Le, Thi Hoa Nguyen, Son Tung Vu, Thien Thang Tran, Minh Hanh Vu, Van Tuan Nguyen, Francesco Ventrella, Anna Belfiore, Antonio Greco, Franco Mastroianni, Salvatore Lenti, Domenico Ruggiero, Michele Cannone, Vincenzo Ostilio Palmieri, Massimo Errico, Giuseppe Mancia, Guido Grassi, Sverre E. Kjeldsen
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413641894