Work

Immune microenvironment and fibroblast subpopulation in diabetic wound healing

Year: 2025

Type: article

Abstract: subpopulations. Fluorescence imaging confirmed these transcriptional changes at the protein level. This comprehensive profiling of the DFU repair microenvironment uncovers specific immune-fibroblast interactions that may underlie healing impairment, offering new directions for targeted therapeutic development.

Source: iScience

DOI: 10.1016/j.isci.2025.113440

Authors: Jing Gan, Yuanrong Chen, Lu Tang, Hui Dong, Xiaotang Gao, Yunfeng Huang, Yang Pan, Jing Hong, Zhibiao Bai, Xiong Chen, Zhuofeng Lin, Hong Zhu

Institutions: Guangdong Medical College, First Affiliated Hospital of Wenzhou Medical University, Wenzhou Medical University

Language: English

Topic: Wound Healing and Treatments

Subfield: Rehabilitation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: Special Funds for the Basic Research and Development Program in the Central Non-profit Research Institutesof China, Science and Technology Program of Zhejiang Province

Awards: G5170715570, G6085203515

OpenAlex ID: W4413655418

FWCI: 4.926

Cites: 74

Cited by: 16

Related to: 10