Work

Cholesterol Granuloma of the Frontal Sinus Complicated by Mycetoma: A Rare Case Report

Year: 2025

Type: article

Abstract: Cholesterol granuloma is an uncommon inflammatory lesion whose etiology is still unclear. It is thought to originate from blood accumulation in a pneumatized space, probably after bleeding. The most frequent site is the petrous apex of the temporal bone, whilst it is very uncommon in the paranasal sinuses. We present a clinical case of an 80-year-old female patient with intense frontal headache and diplopia who underwent a neuro-navigated endoscopic sinus surgery. The histological diagnosis was a cholesterol granuloma of the frontal sinus, contaminated by Aspergillus Fumigatus hyphae. Cholesterol granuloma of the frontal sinus is a rare finding in clinical practice, but it should be taken into account in the diagnostic path in presence of rapidly increasing sight alterations and headache, even without rhinological symptoms.

Source: Sinusitis

DOI: 10.3390/sinusitis9020015

Authors: Chiara Rustichelli, Alessandro Serrone, Giovanni Cavallo, Antonino Maniaci, Gian Luca Fadda

Institutions: Ospedale San Luigi Gonzaga, University of Turin, Università degli Studi di Enna Kore

Language: English

Topic: Sinusitis and nasal conditions

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,207