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Síntesis Eficiente de δ-Decalactona Enantioméricamente Pura: un Enfoque Ecológico a Partir de Quirones Naturales

Year: 2025
Type: article
Abstract: An innovative approach presents for the synthesis of enantiomerically pure δ-decalactone, using the lactone 7,3-LXF as a precursor. Highly selective reactions such as furan opening, diasteroselective allylation, and Corey-Winter olefination led to 6, which upon hydrogenation gives d-lactone. The overall yield was 51%. Tetrahydro-6-(1-penten-1-yl)-2H-pyran-2one was also obtained, opening new possibilities in lactone chemistry.
Language: English
Field: Chemistry
Open Access status: hybrid
OpenAlex ID: W4413769232
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