Year: 2025
Type: article
Study design: Case Report
Abstract: is a gram-negative anaerobic bacterium commonly associated with periodontal disease. However, its role in extraoral infections, particularly in immunocompetent individuals, is increasingly recognized. We report a rare case of hepatorenal abscess caused by F. nucleatum in a previously healthy woman, initially suspected to have a malignant tumor based on PET-CT findings. Next-generation sequencing (NGS) of abscess aspirate confirmed the pathogen. The patient responded well to targeted antibiotic therapy. This case highlights the importance of considering anaerobic pathogens in deep-seated abscesses and the utility of NGS in achieving accurate microbial diagnosis.
Source: Frontiers in Medicine
Authors: Lei Jin, Changkang Chen, Hong Zhao, Lei Chen, Xian Wang, Qin Wang, Ji Yuan, Jinjin Li, Shen Xu, Runzhen Zhang, Wenwen Chu, Naifang Ye, Guizhou Zou, Jun Ye
Language: English
Subfield: Endocrinology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,801
Funder: Anhui Medical University
Award: G6261921340
OpenAlex ID: W4413776462