MDS-1141: APPULSE-PNH: Oral Iptacopan Monotherapy Demonstrates Clinically Meaningful Hemoglobin (Hb) Increases in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) and Hb≥10 g/dL on Anti-C5 Therapy
Year: 2025
Type: conference-abstract
Authors: Austin Kulasekararaj, Flore Sicre de Fontbrune, Anna Gaya, Ilene Weitz, David J. Kuter, David J. Araten, Bhumika J. Patel, Abhay Singh, Jun Ho Jang, Richard J. Kelly, Eros Di Bona, Michael Loschi, Vinod Pullarkat, Jörg Schubert, Alessandro M. Vannucchi, Mustafa N. Yenerel, Régis Peffault de Latour, Navin Mahajan, Luca Monaco, Tao Ding, Tomasz Lawniczek, Philippe Ferber, Marion Dahlke, Antonio M. Risitano
Institutions: National Institute for Health and Care Excellence, European Society for Blood and Marrow Transplantation, NIHR Wellcome Trust Southampton Clinical Research Facility, King's College Hospital, European Society for Blood and Marrow Transplantation, Hospital Clínic de Barcelona, University of Southern California, USC Norris Comprehensive Cancer Center, Harvard University, Massachusetts General Hospital, NYU Langone Health, New York University, Prisma Health, Cleveland Clinic, Samsung Medical Center, Sungkyunkwan University, St James's University Hospital, Ospedale San Bassiano, Université Côte d'Azur, Centre Hospitalier Universitaire de Nice, City Of Hope National Medical Center, University Hospital Carl Gustav Carus, Technische Universität Dresden, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Istanbul University, Université Paris Cité, Assistance Publique – Hôpitaux de Paris, Novartis (Switzerland), Azienda Ospedaliera S.Giuseppe Moscati, University of Naples Federico II
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W4413781572