Work

Ortho-Carborane-Supported Hypervalent Iodine(III) Reagents: A Scaffold for Enhanced Oxidative Capability

Year: 2025

Type: article

Abstract: The first C-bound ortho-carborane (oCb) supported hypervalent iodine(III) -IL 2 type species are reported in RoCb-IL 2, for L = F and OTf, including two structurally verified -IF 2 examples. Initial synthetic observations and supporting theoretical calculations suggest that the new oCb-IL 2 type compounds will be more reactive than any known Ar-IL 2 compound. This is exemplified by a previously unobserved oxidative demethylation of trimethylsilyl fluoride, suggesting that many substrates unreactive toward Ar-IL 2 could be susceptible to oxidation by oCb-IL 2 .

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.5c10358

Authors: Marcus Sceney, Keith F. White, Jason L. Dutton

Institution: La Trobe University

Language: English

Topic: Boron Compounds in Chemistry

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funder: Australian Research Council

Awards: Finding the limits of oxidative capacity in hypervalent iodine chemistry, C-H to C-F using electrochemistry and gold catalysis