Work

Systematic interventions based on the stress-induced situation, affective, bodily, and cognitive reactions framework to mitigate psychological distress in lung cancer patients post-thoracoscopic surgery: a randomized clinical trial

Year: 2025

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Objective: To evaluate the efficacy of a multi-component intervention based on the Situational, Affective, Bodily, and Cognitive (SABC) stress-response model in reducing psychological distress and enhancing quality of life among post-thoracoscopic lung-cancer patients. Methods: = 120) by means of computer-generated, sealed-envelope allocation. Outcome assessors were blinded to group assignment. The intervention comprised psycho-education, SABC-based skills training, a daily-habits checklist and scheduled follow-up. Psychological distress was measured with the NCCN Distress Thermometer (DT); quality of life was assessed with the EORTC QLQ-C30 at baseline and at 1, 3, 6, and 12 months post-surgery. Linear mixed-effects models were used, under both intention-to-treat (ITT) and per-protocol analyses, to test time-by-group interactions. Results: > 0.05). Conclusion: A structured SABC-informed intervention significantly improves functional domains and reduces psychological distress in early-stage lung-cancer survivors after thoracoscopic surgery. Limitations include recruitment from a single tertiary center and exclusion of patients with severe comorbidities, which may limit generalisability to broader clinical populations. Clinical Trial Registration: A randomized controlled trial of a psychological-distress intervention in patients with lung cancer based on the SABC framework. https://www.chictr.org.cn/searchproj.html?title=&officialname=&subjectid=®status=®no=ChiCTR1900028487&secondaryid=&applier=&studyleader=&createyear=&sponsor=&secsponsor=&sourceofspends=&studyailment=&studyailmentcode=&studytype=&studystage=&studydesign=&recruitmentstatus=&gender=&agreetosign=&measure=&country=&province=&city=&institution=&institutionlevel=&intercode=ðicalcommitteesanction=&whetherpublic=&minstudyexecutetime=&maxstudyexecutetime=&btngo=btn, identifier: ChiCTR1900028487.

Source: Frontiers in Psychology

DOI: 10.3389/fpsyg.2025.1511622