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Impact of obesity on clinical outcomes of v-NOTES hysterectomy: a retrospective study

Year: 2025

Type: article

Abstract: Background: Obesity is a global health challenge that complicates gynecological surgery. Vaginal natural orifice transluminal endoscopic surgery (v-NOTES) offers a minimally invasive approach to total hysterectomy (TH), but its safety and efficacy in obese patients remain underexplored. Objective: This study aimed to assess the impact of obesity on the perioperative and clinical outcomes of v-NOTES hysterectomy, accounting for potential confounders. Methods: = 99). Intraoperative indicators and postoperative outcomes during hospitalization, including operative time, intraoperative blood loss, gastrointestinal recovery, hospital stay, and postoperative complications, were compared. A multivariable regression analysis was used to adjust for confounders. All patients were followed up during hospitalization and at 2 and 6 weeks postoperatively. Results: > 0.05). Conclusion: v-NOTES hysterectomy is a safe and effective option for obese patients, with comparable complication rates to non-obese patients. However, obesity independently contributes to longer operative times and delayed recovery. Targeted perioperative strategies, particularly for improving gastrointestinal recovery, could enhance outcomes in this population.

Source: Frontiers in Medicine

DOI: 10.3389/fmed.2025.1619188

Authors: Liu Yang, Wang Qilin, Lian Haiying, Pan Feng, Li Tao, Li Junqiang