Breast cancer metastasizing to the stomach, A challenging diagnosis in stomach cancer: A Case Report and Literature Review
Year: 2025
Type: article
Study design: Case Report
Abstract: Objective: This case report presents a 63-year-old female patient diagnosed with gastric metastasis from breast ductal carcinoma, highlighting the importance of recognizing gastrointestinal symptoms in breast cancer survivors. Case: A detailed case history, imaging studies (abdominal MRI), and endoscopic assessments were performed, complemented by histopathological and immunohistochemical evaluations. Imaging revealed thickening of the stomach wall, and endoscopy confirmed thickened gastric rugae. Microscopic examination showed solid islands, pleomorphic tumor infiltration, and occasional gland-like structures. Immunohistochemistry demonstrated positivity for pancytokeratin, estrogen receptor, progesterone receptor, and mammaglobin, confirming metastatic breast cancer. Conclusion: Gastric metastasis from breast cancer is often overlooked due to nonspecific gastrointestinal symptoms. Awareness of this rare complication is critical for timely diagnosis and management in patients with a history of breast malignancy
Source: Medical Science and Discovery
Authors: Ahmet Midi, Abdullah Şimşek, Ayşe Nimet Karadayı
Institutions: Altınbaş University, Maltepe University, Okan University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413817907