Work

Potential application of nanotechnology in Type-3 diabetes: Bridging insulin resistance and neurodegeneration

Year: 2025

Type: article

Abstract: This review explores the emerging concept of Type-3 diabetes (T3D), an unconventional classification linking insulin resistance with neurodegenerative processes. It explores the intricate molecular mechanisms underlying this association and highlights the importance of early diagnosis for effective intervention. The tale emphasizes the central role of nanomaterials (NMTs) in transforming diagnostic and therapeutic strategies for T3D. Nanoparticles (NPs), nanosensors, and quantum dots (QDs) have emerged as effective tools enabling the precise detection of relevant biomarkers and facilitating early disease identification. Additionally, the multifunctionality of NMTs opens avenues for targeted drug delivery (DD) and imaging modalities, promising a holistic approach to treatment. The integration of nanotechnology enhances diagnostic accuracy and presents innovative therapeutic modalities, ushering in T3D management, which is entering a new era. This comprehensive exploration underscores the potential of NMTs in reshaping our understanding and clinical approaches to this intricate intersection of metabolic and neurodegenerative disorders.

Source: Nano Trends

DOI: 10.1016/j.nwnano.2025.100144

Authors: Adrija Ghosh, Sresha Sarkar, Debashmita Mandal, Jonathan Tersur Orasugh, Suprakas Sinha Ray, Dipankar Chattopadhyay

Institutions: University of Calcutta, Council for Scientific and Industrial Research, University of Johannesburg

Language: English

Topic: Nanotechnology research and applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000