Work

Preregistration: A Key to Credible Real‐World Evidence Generation

Year: 2025

Type: article

Abstract: BACKGROUND: Preregistration of study protocols in a public repository promotes transparency and reproducibility in pharmacoepidemiological research. Despite its clear benefits, preregistration remains underutilized. PURPOSE: Here, we discuss the advantages of preregistration, explore barriers to its implementation, and highlight existing repositories for preregistering real-world evidence study protocols. A relatively new option is the Real-World Evidence Registry within the Open Science Framework (OSF), which we briefly introduce.

Source: Pharmacoepidemiology and Drug Safety

DOI: 10.1002/pds.70215

Authors: Emma Simonsen, Shirley V. Wang, Helene Kildegaard, Anton Pottegård

Institutions: University of Southern Denmark, Brigham and Women's Hospital, Harvard University, Rigshospitalet

Language: English

Topic: Research Data Management Practices

Subfield: Information Systems

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,650