The Advantages of The Alpha-Glycosylated Form of Hesperidin, Increased Bioavailability and Beneficial Effects for Human Health
Year: 2024
Type: article
Abstract: Hesperidin is a bioflavonoid found in high concentrations in citrus fruits.It benefits cardiovascular function, type II diabetes, anti-inflammation, and cutaneous functions, including wound healing, UV protection, anti-inflammation, antimicrobial, anti-skin cancer, and skin lightening.It has low water solubility and poor oral bioavailability.To improve its solubility and bioavailability, Alpha-Glucosyl Hesperidin (AGH) has been synthesized from hesperidin by transglucosylase using cyclodextrin glucotransferase.It is 10,000×more soluble and has 3.7×higher bioavailability than hesperidin.AGH has various pharmacological effects, such as hypolipidemic and hypouricemic effects, and may therefore be a useful supplement or drug for people who are fighting with obesity and fat loss.In this review we summarize the potential benefits of alpha-glucosyl hesperidin and add points for safety and hesperidin use from a commercial point of view.
Author: Eva Künnemann
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4413839336