Hr-lcms Profiling and Cytotoxicity Study of Crude Aqueous Extract of Phaseolus Vulgaris Linn. Leaves
Year: 2025
Type: article
Abstract: The objective of the current study is to evaluate the phytochemical profile and cytotoxic properties of the crude aqueous extract of Phaseolus vulgaris Linn.leaves.This plant is well-known for its nutritional and agricultural benefits, and its crude extract was obtained through the sequential extraction method.The extract was then subjected to High-Resolution Liquid Chromatography-Mass spectrometry (HR-LCMS) analysis to identify the phytoconstituents present.A total of 120 phytoconstituents were obtained, with 26 compounds being identified as major constituents in both positive and negative ESI modes.Sapropterin, Melibiose, Pirbuterol, Osmaronin, N-Isovalerylglycine methyl ester, Beta-D-Galactopyranosyl-(1->4) -beta-D-galactopyranosyl-(1->4) -D-galactose, 3-Methyladenine, 3-Beta, 6-Beta-Dihydroxynortropane, D-pipecolic acid, Lotaustralin, 8-Hydroxyadenine, L-threo-3-Phenylserine, L-isoleucyl-L-proline, Gentianadine, L-Arogenate, Prolyl-Arginine, Norcotinine, Ganolucidic acid E, Benzocaine, Succinoadenosine, D-Galactonate, Melibiose, Thiolactomycin, (Z)-5-[(5-Methyl-2-thienyl)methylene] -2(5H) Furanone, Rutin, and Kuwanon Z.The toxicity of crude extracts at various concentrations was
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4413843265