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Adherence to EAT-Lancet diet and odds of irritable bowel syndrome and functional dyspepsia: the Isfahan functional disorders (ISFUN) study

Year: 2025

Type: article

Abstract: BACKGROUND: No study has been conducted to investigate the association between adherence to the EAT-Lancet diet and odds of irritable bowel syndrome (IBS) and functional dyspepsia (FD). This cross-sectional study was aimed to assess the association between adherence to the EAT-Lancet diet and odds of IBS and FD. METHODS: This cross-sectional analysis was done among 1892 Iranian apparently healthy adults, aged 18 to 65 years, in Isfahan, Iran. Usual dietary intakes of participants were assessed using a validated Dish-based, 106-item food frequency questionnaire. To measure participants' adherence to the EAT-Lancet diet, the EAT-Lancet diet index (ELD-I) was calculated. IBS and FD were assessed using ROME IV criteria. RESULTS: In total, 5.29% and 3.17% of participants had IBS and FD, respectively. The mean age of study participants was 39.64 ± 10.24 years, and the mean BMI was 27.08 ± 4.91 kg/m². After adjustment for potential confounding factors, a significant positive association between lower adherence to the EAT-Lancet diet and odds of IBS was revealed (OR: 1.74; 95% CI: 1.00-3.04), but not for FD (OR: 1.37; 95% CI: 0.65-2.89). CONCLUSION: A significant positive association was observed between lower adherence to EAT-Lancet diet and odds of IBS. More prospective studies are needed to affirm these associations.

Source: Nutrition Journal

DOI: 10.1186/s12937-025-01195-5

Authors: Asma Salari-Moghaddam, Awat Feizi, Parisa hajihashemi, Alireza Ani, Hamidreza Roohafza, Peyman Adibi

Institutions: Medical University of Ilam, Isfahan University of Medical Sciences

Language: English

Topic: Gastrointestinal motility and disorders

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,190