Year: 2025
Type: article
Study design: Case Report
Abstract: SclerEDEMA is a rare condition marked by diffuse skin thickening, often confused with sclerODERMA. It is linked with infections, malignancies, and diabetes. Although scleredema is associated with hematologic malignancies like multiple myeloma, it has not been reported with breast cancer, as suspected in this patient. We present a case of a patient diagnosed with scleredema, confirmed through skin biopsy. Subsequent cancer screenings identified a 6 mm breast nodule, which was confirmed as grade 3 ductal carcinoma. This newfound association between scleredema and breast cancer highlights the importance of vigilant health maintenance and regular cancer screenings in these patients.
Authors: Jenifer Centeno Gavica, Rupak Thapa
Institution: Atrium Health Wake Forest Baptist
Language: English
Topic: Skin Diseases and Diabetes
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4413846277