Work

AI-driven engineering of EgtD enabling high-efficiency ergothioneine synthesis with a multi-enzyme cascade

Year: 2025

Type: article

Source: International Journal of Biological Macromolecules

DOI: 10.1016/j.ijbiomac.2025.147266

Authors: Yamiao Li, Jingxin Rao, Zhentao Jiang, Xinyi Zhang, Qiang Zhu, Caokai Zhu, Wenli Yu, Xin Dong, Shanshan Gao, Wenchi Zhang, Liang Lin, Mingyue Zheng, Rongzhen Zhang

Institutions: Jiangnan University, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, Johns Hopkins University, Johns Hopkins Medicine, Shanghai Institute of Organic Chemistry

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, Ministry of Science and Technology of the People's Republic of China, Ministry of Human Resources and Social Security, National Key Research and Development Program of China, Project 211

Awards: G1698624078, G2613978157, G481796789, G8527797827

OpenAlex ID: W4413848902

FWCI: 1.567

Cites: 53

Cited by: 6

Related to: 10