Work

Potential of Green Synthesis of Silver and Gold Nanoparticles for the Management of Metabolic Associated Steatotic Liver Disease: A Mini Review

Year: 2025

Type: article

Abstract: Metabolic-associated steatotic liver disease is a metabolic disorder with limited pharmacological treatment options and only one approved medication to date. MASLD can be asymptomatic in its earlier stage and hence, prevention of this disease progression is the most effective approach. Recently, green-synthesized nanoparticles, particularly silver (AgNPs) and gold nanoparticles (AuNPs), have gained interest due to their eco-friendly production, biocompatibility, and bioactive properties. This review highlights the biosynthesis of AgNPs and AuNPs using medicinal plant extracts and their reported biological effects relevant to MASLD management including anti-hyperlipidemic, anti-diabetic, antioxidant and anti-inflammatory activities. While findings are promising, further mechanistic studies and preclinical validation are required to facilitate their use as targeted therapies for MASLD.

Source: ASEAN Journal on Science and Technology for Development

DOI: 10.61931/2224-9028.1633

Authors: Atiqah Suhaili, Ya Chee Lim, Mei Ann Lim, Lee Hoon Lim, Mohammad Mansoob Khan, Monowarul Mobin Siddique

Institutions: Universiti Brunei Darussalam, University of Utah

Language: English

Topic: Nanoparticles: synthesis and applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Universiti Brunei Darussalam, Kementerian Pendidikan