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Ketamine infusion therapy in an elderly patient with complex regional pain syndrome and major depression

Year: 2025

Type: article

Abstract: Complex regional pain syndrome (CRPS) is a chronic pain disorder that severely affects mobility and quality of life. This case report describes an 86-year-old man who has a long-standing history of CRPS-related back and leg pain. Traditional treatments, including opioids and duloxetine, did not improve his symptoms, and due to religious beliefs restricting specific interventions, standard hospital care was limited. Given the severity of his symptoms and the refractory nature of his condition, an intravenous ketamine infusion was recommended to improve pain and comorbid depressive symptoms. Following one treatment, the patient exhibited immediate and substantial improvements in pain intensity, mood, and mobility. This case accentuates the importance of culturally sensitive, patient-centered care and suggests the role of ketamine in treating CRPS when traditional therapies are ineffective.

Source: International Journal of Community Medicine and Public Health

DOI: 10.18203/2394-6040.ijcmph20252868

Authors: Parinda Parikh, Jeremy Kays, Zoe Gellert, Shaurya K. Singh, Alisha A. Alphonse, Himani J. Suthar, Aatish D. Bhatta, Arnesh Shukla, Parthiv Pansuriya, Arushi K. Chandra, Mahiya Buddhavarapu, Mina Oza

Institutions: Weill Cornell Medicine, Windsor University School of Medicine, Tulane University, Pravara Institute of Medical Sciences, St. George's University, KIST Medical College, St. Martinus University, Government Medical College, New York University, University of Pittsburgh

Language: English

Topic: Pain Management and Treatment

Subfield: Anesthesiology and Pain Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413853681

FWCI:

Cites: 8

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Related to: 10