Work

Biological age on pause. The effect of nutraceuticals on endothelial dysfunction and aging processes

Year: 2025

Type: article

Abstract: Aging is an inevitable process that includes an imbalance between antioxidant defenses and reactive oxygen species, changes in protein and mitochondrial turnover, telomere shortening, cellular senescence, epigenetic changes, and stem cell exhaustion. These conditions are associated with mild to moderate inflammation, which always accompanies the aging process and age-related diseases. The results of numerous studies indicate the existence of a complex biomolecular mechanism associated with age-related vascular dysfunction, which leads to oxidative stress, vascular remodeling, and endothelial dysfunction.

Source: Medical alphabet

DOI: 10.33667/2078-5631-2025-19-35-45

Authors: S. V. Orlova, E. V. Prokopenko, E. A. Nikitina, N. V. Balashova

Institutions: Peoples' Friendship University of Russia, Invicro (United States), Moscow Regional Scientific Research Clinical Institute. MF Vladimirsky

Language: English

Topic: Nitric Oxide and Endothelin Effects

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4413862662

FWCI:

Cites: 151

Cited by:

Related to: 10