Sociodemographic, Clinicopathological, and Short-term Treatment Outcome Analysis of Cancer Cervix Uteri Patients at a Teaching Institution
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: In developing countries like India, the burden of cervical cancer remains high, mostly due to limited access to screening methods as well as treatment.It is the leading cause of cancer deaths in women due to late presentation and diagnosis.This study aims to analyze the sociodemographic and clinical profile of cervical cancer patients and their short-term treatment outcome.Methods: A prospective observational study included all histopathologically confirmed cases of cancer cervix at a teaching Institution in Delhi, India, over a period of two years.Results: A total of 120 cases of cancer cervix uteri were analyzed.The mean age of the participants was 53 ± 10.84 years.The average age of menarche was 13.97 ± 0.882 years.The average age of menopause was 45.46 ± 4.325 years.Mean age of coitarche was 16.5 years ± 2.251.The mean age of first childbirth was 18.08 years ± 2.74.Alcohol intake was the risk factor affecting 21.7% of partners, and 73.3% did not use any form of contraception.A family history of cancer was there in 13.3% cases.Cervical growth was found in 91.7% patients.The most common stage was IIIC1 (33.3%), histopathological type was squamous cell carcinoma (SCC) (98.3%), and variety was large cell keratinizing squamous cell cancer (LCKSCC) (41.7%).Primary radiotherapy was required in 80%, surgery in 5%, and palliative treatment in 15% of cases.For radiotherapy, the mean time required from diagnosis to treatment was 6.94 ± 3.49 weeks.The primary treatment outcome, complete response, was achieved in 62.75% cases.Conclusion: Early detection and prevention of the progression of cancer cervix uteri are required in India.The facilities for radiotherapy treatment are to be enhanced in Delhi, India, for better treatment outcomes of cases.
Authors: Preeti Singh, Asmita M Rathore, Sarah Mirza, Latika Sahu, Rakshitha Yadav
Institution: Maulana Azad Medical College
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4413869504