Comparative Evaluation of Erosive Impact of Pediatric Drugs on Primary Tooth Enamel: An In Vitro Study
Year: 2025
Type: article
Abstract: a correlation between the use of antibiotics and the prevalence of Streptococcus mutans, the principal microbe that causes dental caries, in children aged one to three, which is considered to be the most critical period for bacterial acquisition.4 When chronic diseases are treated with medications that have a long oral clearance, dental erosion may become a problem.These children may utilize liquid medication formulations on a daily basis.Although some medications' active chemicals are essential for maintaining or enhancing health, some of their inactive constituents can be harmful, such as causing tooth erosion and cavities.5 The erosive potential of pediatric syrups has been measured in a limited number of investigations.Hence, the present study was conducted to evaluate the erosive effects of three pediatric medications on primary tooth enamel. IntroductIonThe gradual loss of dental hard tissues due to chemical disintegration without bacterial involvement is known as dental erosion.Dental erosion has become more common in modern culture as a result of shifting lifestyles, particularly among children and adolescents.Erosive tooth wear is a multifactorial irreversible process that may be caused by intrinsic, extrinsic, or idiopathic factors. 1 The intrinsic etiologic factors are related to the contact of tooth tissues with stomach acids (i.e., regurgitation and reflux disorders).Although acidic medications and behavioral variables have also been identified as extrinsic etiologic factors in tooth erosion, increased consumption of acidic foods and beverages has emerged as the main extrinsic source of dental erosive agents. 2 Children who have problems swallowing pills and capsules are frequently prescribed liquid medications.Typically, liquid medications are available in a variety of formats, such as syrups, suspensions, and solutions.Acids are typically added to syrup to maintain its consistency and serve as buffering agents, which also guarantees the syrup's compatibility.Dental erosion is a result of many syrups' low pH, which is below 5.5. 3 The morphologies of primary and permanent dental enamel differ; primary enamel is less mineralized and has a distinct structural arrangement.As a result, when exposed to an acidic environment, the primary enamel is more vulnerable to degradation.The tongue, lips, and cheek are additional anatomical components that contribute to the spread of erosion.Saliva also plays a significant part in erosion.Additionally, research has shown
Source: World Journal of Dentistry
Author: Adel S Alqarni
Institution: Prince Sattam Bin Abdulaziz University
Language: English
Topic: Dental Erosion and Treatment
Subfield: Orthodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413878202