Year: 2025
Type: preprint
Abstract: Nickel-catalyzed hydroarylation allows a completely atom-economical approach by the catalytic union of alkynes and polyfluorinated arenes through a ligand-to-ligand hydrogen transfer (LLHT) mechanism. To enable application of this process in oligomerizations and polymerizations, we studied the influence of catalyst, ligand, and substrate structure to control regioselectivity and optimize yields towards a single reaction outcome. These findings were applied in 2:1 alkyne:arene couplings to develop model conditions and were then further evaluated in preliminary applications of step-growth polymerizations.
Source: ChemRxiv
Institution: University of Michigan
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W4413879026