Year: 2025
Type: article
Study design: Case Report
Abstract: Desensitization is an immunological process that creates temporary tolerance to a drug, which disappears once treatment is discontinued. Ciprofloxacin is a commonly used antibiotic, particularly for chronic lung diseases, yet there are very few desensitization protocols for it. Two ciprofloxacin desensitization schemes were developed a long time ago. However, these protocols are multistep, time-consuming processes, due to which a new protocol is required. We would like to present the practical oral desensitization protocol that we use. We included two patients with cystic fibrosis and bronchiectasis who required ciprofloxacin due to the presence of Pseudomonas aeruginosa in their sputum cultures. The desensitization process was successful and well-tolerated. This protocol is important because it addresses a significant gap in the literature.
Source: Allergologia et Immunopathologia
Institution: Sağlık Bilimleri Üniversitesi
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,000
OpenAlex ID: W4413879764