Work

Massive Radionecrosis vs Pseudoinflammation After Radiosurgical Corpus Callosotomy in a Patient With Drug-Resistant Epilepsy

Year: 2025

Type: article

Abstract: Radiosurgery (RS) has proven to be an effective alternative for the treatment of intracranial neoplasms, arteriovenous malformations, and functional conditions such as epilepsy. Regarding the latter, palliative epilepsy surgery involving corpus callosum disconnection by RS has been shown to be as effective as its surgical counterpart in terms of seizure reduction. However, adverse effects derived from radiation-induced neurotoxicity in the target area may occasionally occur, with radionecrosis (RN) being one of the main causes of morbidity after RS. This paper presents the case of a female patient diagnosed with refractory epilepsy who developed an extensive heterogeneous lesion evident on MRI studies months after undergoing callosotomy by RS.

Source: Cureus

DOI: 10.7759/cureus.91429

Authors: Juan Romero Valencia, Sergio Moreno Jiménez, Guillermo Axayacalt Gutierrez-Aceves, Martha Lilia L Tena Suck, Emilio García Gómez

Institutions: Instituto Nacional de Neurología y Neurocirugía, Centro Médico ABC

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413885681