Year: 2025
Type: article
Abstract: Drug delivery often faces challenges from biological barriers, including the skin and mucosa. Penetration enhancers (PEs) are commonly employed to improve the delivery of poorly permeable drugs. Among them, volatile oils derived from natural plants have emerged as promising candidates due to their rapid action, minimal side effects, and high efficiency. This paper provides a brief introduction to biological barriers and highlights the potential of volatile oils as PEs and their underlying mechanisms. Their role in improving transdermal and transmucosal drug delivery has been explored by a comprehensive review of recent research, which provides valuable insights into their future application in pharmaceutical formulations.
Source: Pharmaceutical Fronts
DOI: 10.1055/a-2658-2217
Authors: Xinyu Ma, Yu Jin, Miao Wang, Shiyu Zong, Yunlong Cheng, Hong Zhang, Wei Wu, Yi Lu, Ye Li, Chunliu Wang
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4413890057