Long-Term Gastrointestinal Outcomes in Patients on Teduglutide: A Propensity-Matched Analysis
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Teduglutide, a glucagon-like peptide-2 (GLP-2) analogue, promotes intestinal adaptation in patients with short bowel syndrome requiring parenteral nutrition (PN). While its benefits in reducing PN dependence are well-documented, concerns persist regarding its long-term gastrointestinal (GI) safety, particularly the potential risks of colon polyps, neoplasia and small bowel (SB) obstruction. Understanding these risks is critical for optimizing treatment strategies and ensuring patient safety.
Source: Intestinal failure.
Authors: Khuloud Abu Tair, David Hakimian
Institutions: Hebrew University of Jerusalem, Hadassah Medical Center
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,750
OpenAlex ID: W4413897061