Demographic and clinical insights into Stage IV breast cancer: a comparative approach to surgical versus non-surgical treatment outcomes
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Cancer is a major global health challenge, with breast cancer remaining a leading cause of mortality. Stage IV breast cancer, marked by metastasis to distant organs, is particularly complex and is often managed as incurable. Effective treatment decisions are guided by the TNM staging system, though more nuanced approaches are essential to improve patient outcomes. Methods: This retrospective observational study evaluates the demographic and clinical factors associated with Stage IV breast cancer, focusing on the impact of surgical intervention on patient outcomes. The study includes 215 Stage IV breast cancer cases, analyzing clinical variables such as age, reproductive history, hormone receptor status, lymph node involvement, and treatment modalities. Patients are categorized based on whether they received surgical or non-surgical interventions. Results: Among the study population, those who underwent surgery showed statistically significant differences in survival rates and quality of life compared to those who opted for non-surgical treatment. The analysis highlights critical factors like hormone receptor status and lymph node involvement that influence treatment outcomes, providing insights into the potential benefits of surgery even in Stage IV cases. Conclusion: This study underscores the role of surgical intervention as part of a tailored approach to managing Stage IV breast cancer. The findings contribute to a better understanding of factors influencing treatment choices and outcomes, supporting more informed decision-making in clinical practice.
Source: Annals of Medicine and Surgery
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,850
OpenAlex ID: W4413905499