Supplementary Figure S4 from Kinome Reprogramming of G2/M Kinases and Repression of MYCN Contribute to Superior Efficacy of Lorlatinib in ALK-Driven Neuroblastoma
Year: 2025
Type: supplementary-materials
Abstract: Supplementary Figure S4 shows that COG-N-424x, a wild type ALK PDX, does not downregulate G2/M kinases upon ALK inhibition.
Authors: Smita Matkar, Michael P. East, Timothy J. Stuhlmiller, Gabriela M. Witek, Alvin Farrel, Steven Pastor, Denis O. Okumu, Anne Kennedy, Joshua R. Kalna, Esther R. Berko, Colleen E. Casey, Kateryna Krytska, Khushbu Patel, Jo Lynne Rokita, Mark Gerelus, John M. Maris, Gary L. Johnson, Yael P. Mossé
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4413905943