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Supplementary Figure S1 from The Discovery and Characterization of HBS-101, a Novel Inhibitor of Midkine, as a Therapeutic Agent for the Treatment of Triple-Negative Breast Cancer

Year: 2025

Type: supplementary-materials

Abstract: Supplementary Figure S1: A. Boxplots of MDK gene expression in normal (n = 403) and BC tumor (n = 1097) gene array data (https://tnmplot.com/analysis/). B, Expression of MDK in breast invasive carcinoma based on BC subclasses. C, Expression of MDK in major subclasses of TNBC (https://ualcan.path.uab.edu/.). D, Survival analysis using Xena Functional Genomics Explorer Breast Cancer (Chin 2006) data set shows association of high MDK gene expression with poor survival in BC patients.

DOI: 10.1158/1535-7163.30028864

Authors: Megharani Mahajan, Alondra L. Rodriguez Sanchez, Sridharan Jayamohan, Dileep K. Vijayan, Jessica D. Johnson, Huan Xie, Yang Wang, Dong Liang, John R. Sanchez, Panneerdoss Subbarayalu, Manjeet K. Rao, Ratna K. Vadlamudi, Gangadhara R. Sareddy, Hareesh B. Nair, Suryavathi Viswanadhapalli

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4413905972

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