Work

Double-Network Hydrogels via Hybrid Strategies: Potential in Large-Scale Manufacturing for Colorimetric Indicator

Year: 2025

Type: article

Abstract: Biological hydrogels are widely available in terms of raw material sources and can be processed and molded using relatively simple techniques. Hydrogels can offer abundant three-dimensional, water-containing channels that facilitate the reaction between gases and dye, making them the preferred choice for the solid support layer in colorimetric indicators. However, biomass hydrogels exhibit inferior mechanical properties, making them unsuitable for large-scale manufacturing processes. In this study, four dual-network composite hydrogels Agar/Gelatin, Sodium Alginate/Agar, Sodium Alginate/Poly (vinyl alcohol), Sodium Alginate/Gelatin (AG/Gel, SA/AG, SA/PVA and SA/Gel) prepared through hybrid strategies. Furthermore, the influence of the dual-network structure on the mechanical properties and ammonia response was systematically investigated, using microscopy and Fourier transform infrared spectroscopy (FTIR) characterization method. The experimental results demonstrate that the incorporation of SA into original hydrogel matrices can significantly enhance both the mechanical and ammonia response performance due to the secondary topological network structure. The interpenetrating double network structure was effectively regulated through the calcium ion cross-linking process. The color difference threshold of SA/PVA's response to ammonia gas is 10, it holds promise for rapid detection applications. The SA/Gel composite hydrogel exhibits excellent mechanical robustness and toughness. The tensile strength of the SA/Gel sample is 11 times that of a single gel, and the toughness is 80 times greater, suggesting its suitability for large-scale manufacturing of colorimetric indicator.

Source: Gels

DOI: 10.3390/gels11090697

Authors: Ningli An, Jiwen Liu, Wentao Zhou, Qing He, Jianan Li, Yali Xiong

Institution: Xi'an University of Technology

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,534

Funder: National Natural Science Foundation of China