Modeling Cellular Processes Using Big Data Integration in Bioinformatics
Year: 2024
Type: conference-paper
Abstract: Adding big data to biology is changing the way we describe how cells work, which lets us make more complete and accurate models of biological systems. With the rise of high-throughput technologies like genetics, transcriptomics, proteomics, and metabolomics, huge amounts of biological data are being produced, which gives scientists a chance to study how cells work like never before. This essay looks at how big data can help us better understand how cells work by focussing on how machine learning, network analysis, and systems biology can be used. Patterns can be found in multi-omic datasets using machine learning algorithms, such as guided and uncontrolled learning. These algorithms help us understand gene regulation, protein interactions, and cellular reactions. Network-based methods improve cellular process modelling even more by building complex networks of molecule interactions that mirror the complicated control systems inside cells. Systems biology and computer simulations provide dynamic models that duplicate how cells behave, which makes it easier to study how diseases work, how drugs work, and how to treat them. Even with these improvements, there are still problems with integrating, scaling, and interpreting data because living systems are very complicated and data is not all the same. The study also talks about how artificial intelligence (AI) can help solve these problems, make predictions more accurate, and make cellular models more useful. Using big data modelling in disease research, like studying cancer and brain illnesses, shows that it can help find signs, make treatment plans better, and move personalised medicine forward. In the end, combining big data with bioinformatics has the huge potential to change how we think about how cells work, opening up new areas for medical study and drug creation.
Authors: Parikshit Mahalle, Anish C M, Sandeep Kumar, Anishkumar Dhablia, Samir N Ajani, Yatin Bharat Gandhi
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4413915569