Work

Hot-Spot-Guided Generative Deep Learning for Drug-Like PPI Inhibitor Design

Year: 2025

Type: article

Source: Interdisciplinary Sciences Computational Life Sciences

DOI: 10.1007/s12539-025-00756-w

Authors: Heqi Sun, Jiayi Li, Yufang Zhang, Shenggeng Lin, Junwei Chen, Hong Tan, Ruixuan Wang, Xueying Mao, Jianwei Zhao, Rongpei Li, Dong-Qing Wei

Institutions: Shanghai Jiao Tong University, State Key Laboratory of Microbial Metabolism, Shanghai Innovation Institute

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Ministry of Science and Technology, National Natural Science Foundation of China

Awards: G2078735520, G2191216477, G3171197127

OpenAlex ID: W4413916627

FWCI: 1.441

Cites: 54

Cited by: 3

Related to: 10