Personalized Approach to the Prognosis and Prevention of Intra-abdominal Adhesions After Appendectomy
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: Rationale: The incidence of acute appendicitis is 708 cases per 10000 population. Postoperative complications after open appendectomy were 2.35 to 10%, after laparoscopic appendectomy from 4.9% to 6.2%. Abdominal interventions are accompanied by the development of intra-abdominal adhesions in 14.0% of patients, after repeated interventions – in 90.0-96.0% of the operated patients.Purpose: To determine the efficacy of anti-adhesion therapy after appendectomy.Materials and methods: 60 patients with acute appendicitis who underwent open appendectomy. Men – 19 (31.7%), women – 41 (68.3%). The control group consisted of 30 (50%) patients who did not undergo prevention of intra-abdominal adhesions in the postoperative period, and another 30 (50%) patients who received anti-adhesion therapy (main group). To calculate the risk of intra-abdominal adhesions after ppendectomy, we have developed an “Assistant program for determining the effectiveness of the treatment method and preventing the development of postoperative intra-abdominal adhesions”.Results: By the method of rating testing, it was established that the highest risk of developing postoperative intra-abdominal adhesions is present in patients who do not receive a set of anti-adhesion measures. Anti-adhesion therapy in patients after appendectomy reduces the risk of intra-abdominal adhesions by 1.97 times, improves the quality of life of operated patients.Conclusion: When performing abdominal operations, it is necessary to form groups of patients with a tendency to the formation of intra-abdominal adhesions, for whom anti-adhesion therapy is indicated in order to reduce the risk of developing an adhesive process in the abdominal cavity.
Institutions: Stavropol State Medical University, Sechenov University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4413960359