Work

Microbiological and Clinical Epidemiology of Lomentospora prolificans infections

Year: 2025

Type: article

Abstract: Lomentospora prolificans (formerly Scedosporium prolificans) is an emerging fungal pathogen, affecting both immunocompromised and immunocompetent individuals. Treatment is difficult due to intrinsic resistance against multiple anti-fungal agents. We describe five patients with L. prolificans infections attending a tertiary care center in South India. Out of the 5 patients, 4 patients presented with deep seated infection, and 1 with disseminated disease. Risk factors included uncontrolled diabetes mellitus, advanced HIV infection, T cell lymphoblastic leukemia, carcinoma breast, and immunosuppressant therapy. L. prolificans as an important causative agent of deep seated and disseminated mycoses among immunocompromised patients.

Source: Indian Journal of Medical Microbiology

DOI: 10.1016/j.ijmmb.2025.100957

Authors: Lydia Jennifer Sumanth, Rajiv Karthik, Anuradha Chandramohan, Aparna Irodi, Rani D. Sahni, Joy Sarojini Michael

Institution: Christian Medical College, Vellore

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,210