Work

Primary adrenal melanoma with extensive metastasis: a case report and literature review

Year: 2025

Type: article

Abstract: Primary adrenal melanoma is an exceedingly rare diagnosis. We present a case of primary left adrenal melanoma with rapid and extensive distant metastasis. The patient underwent a biopsy of the left adrenal tumor, and pathological analysis confirmed malignant melanoma. Immunohistochemical staining revealed positive cytoplasmic reactivity for Melan A, HMB45, and SOX-10. We also review relevant cases reported in the English literature and discuss the diagnostic criteria, differential diagnoses, and potential management strategies.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1654218

Authors: Qi Guo, Dai Shi, Guilai Li, Yue Liu, Guoping Xu

Institutions: Second Hospital of Tianjin Medical University, Tianjin Medical University, Second Affiliated Hospital of Soochow University

Language: English

Topic: Adrenal and Paraganglionic Tumors

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801