Evaluation of the Antibacterial Activity of Mentha Longifolia Essential Oil against Enterococcus faecalis and its Chemical Composition.
Year: 2025
Type: article
Abstract: Background: ) is a multidrug resistant pathogen that can cause persistent infections within the root canal system, which poses major challenges in dentistry and is involved in the majority of endodontic failures. Purpose: and its compounds. Materials and Method: (ATCC 29212) was injected into the canal of all groups, except for the negative control group. After four weeks, the groups were washed with 2 ml of the introduced solutions and sampled by paper point to compare the antibacterial effect of these solutions. Broth microdilution method was used to determine the MIC, while Gas chromatography-mass spectrometry (GC/MS) was used to evaluate the chemical compositions of the essential oil. Data were analyzed based on one-way analysis of variance (ANOVA). Then, pairwise comparisons of groups were performed using Tukey's test. Results: < 0.001). Nineteen compounds were identified in the chemical analysis of M. longifolia, among which Piperitenone oxide (64.68%) and Piperitone oxide (23.68%) were the major compounds. Conclusion: . The highest antibacterial effect of root canal irrigants was observed in 2.5% NaOCl, 2% CHX, 10% essential oil, and normal saline, respectively.
Source: PubMed
Authors: Mohammad Ghazizadeh, Abolfazl Davoodabadi, Sohrab Kazemi, Azadeh Harandi, Maryam Ghasempour
Institution: Babol University of Medical Sciences
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4413969737