Work

Case Report: Two cases of primary pulmonary endobronchial extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue localized in the trachea and bronchus

Year: 2025

Type: article

Abstract: Background: Primary pulmonary extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) localized in the trachea and bronchus is rare and diagnostically challenging due to nonspecific clinical and radiological features. Case description: We present two cases of primary endobronchial MALT lymphoma incidentally diagnosed via bronchoscopy. We assessed the characteristic bronchoscopic finding of endobronchial MALT lymphoma, radiological examinations and overall treatment strategies. Conclusion: This study highlights the importance of considering endobronchial MALT lymphoma as a potential diagnosis. A thorough bronchoscopic evaluation of the central airways, along with appropriate biopsy of suspicious lesions, is crucial. Endobronchial MALT lymphoma should be suspected when targeting multiple widely stalked and smooth submucosal nodules or protrusions, mainly located in the central airways.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1626336

Authors: Lei Sha, Meng-Yao Cai, Min Feng, Chang Dong

Institutions: Dalian Medical University, First Affiliated Hospital of Dalian Medical University

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801