Optic nerve sheath diameter in patients undergoing intracranial tumour resection: Perioperative changes and contributing factors - A prospective observational study.
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background and Aims: Ultrasonographic (USG) optic nerve sheath diameter (ONSD) provides a real-time, non-invasive method for assessing intracranial pressure. This study investigates perioperative ONSD variations and contributing factors in patients undergoing elective intracranial tumour resection. Methods: A prospective observational study was conducted on 94 adults with intracranial tumours, excluding orbital lesions and sellar/suprasellar tumours. Preoperative symptoms, Glasgow coma scale scores, and radiological findings were noted. USG-ONSD was assessed in the transverse and sagittal plane on each eye, with an average of three readings at the following time-points: pre-induction, post-induction, post-extubation, and 24-hour post-tumour resection. The presence of ventriculo-peritoneal (VP) shunt, duration of surgery/anaesthesia, intraoperative position, use of osmotic agents, and complications during surgery were noted. The data were analysed using linear regression and general linear modelling in R software. Results: = 0.028) showed significantly higher values and greater changes, whereas the presence of VP shunt, use of osmotherapy, and sitting position for surgery showed a lower trend of ONSD postoperatively. Conclusion: USG-ONSD demonstrates dynamic changes in patients undergoing intracranial tumour resection. ONSD is affected by the size of the tumour, duration of symptoms, and intraoperative positioning, though the trend is homogenous among supratentorial and infratentorial tumours.
Source: PubMed
Authors: Archana Sharma, Shrikanta Oak, Kavin Devani, Siddhi Sawant, C Manisha, Akshita Sharma
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4413971011