Screening for toxicity of azole fungicides in Caenorhabditis elegans identifies triflumizole as a potent reproductive and developmental toxicant
Year: 2025
Type: article
Abstract: may provide insights into the broader impact of azole fungicides relevant to human health. Exposure to triflumizole, resulted in a significant reduction in brood size as well as a dose-dependent decrease in worm development. Similarly, clotrimazole negatively impacted development, but not reproduction, while ketoconazole had no detrimental effect. Together this suggests further research is urgently needed to explore the impact of azole chemicals on human reproductive health.
Source: PubMed
Authors: Samantha Hughes, Charlotte Koopmans, Majorie van Duursen
Institution: Vrije Universiteit Amsterdam
Language: English
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W4413971652