Work

Extranodal diffuse large B-cell lymphoma of the spermatic cord: The first reported case in Saudi Arabia

Year: 2025

Type: article

Abstract: Primary spermatic cord lymphoma is rare, accounting for 1.6 % of spermatic cord tumors. It typically presents as diffuse large B-cell lymphoma (DLBCL) with aggressive course and poor prognosis. A 53-year-old male presented with progressive left testicular mass over one year. Imaging revealed spermatic cord tumor. Radical orchiectomy and histopathology confirmed stage IV Extranodal DLBCL. Patient received 6 cycles CHOP-R chemotherapy plus 2 additional Rituximab cycles, achieving favorable response despite advanced disease. This case emphasizes importance of early diagnosis, advanced imaging, and multidisciplinary treatment for this rare aggressive malignancy.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103199

Authors: Basmah Z. Al Ghanim, Hussain A. Al Ghanim, Erum M. Alhumood

Institutions: Imam Abdulrahman Bin Faisal University, Qatif Central Hospital

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160