Work

The Essentials of Cell-Mediated Immunity Assays for the Management of CMV Infection after Solid Organ Transplantation

Year: 2025

Type: article

Abstract: Provided that cell-mediated immunity (CMI) is known to be vital in managing CMV infection post-transplant along with improving methods to predict the development of cytomegalovirus (CMV) following transplant, CMV-specific-cell-mediated immunoassays have been developed, commercially and research based, to be used in conjunction with pre-transplant CMV serological testing and prophylaxis to help tailor an individual care plan post-transplant. In this review, we assess the status of CMV CMI assays, and their potential uses in solid organ transplant recipients, including benefits and limitations.

Source: OBM Transplantation

DOI: 10.21926/obm.transplant.2503256

Authors: Alexis Guenette, Valentina Stosor

Institution: Northwestern University

Language: English

Topic: Cytomegalovirus and herpesvirus research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413994334