Year: 2025
Type: article
Abstract: This study presents a comprehensive bibliometric analysis of the literature on botulinum toxin A (BoNT‑A) applications in cerebral palsy (CP) between 2005 and 2024. A search conducted in the Web of Science Core Collection identified 690 publications (550 original research articles and 140 reviews). An overall increase in publication output was observed over the years, peaking in 2018, with a temporary decline noted in 2020–2021. The United States, Australia, and Italy were the leading contributors, with Australia achieving the highest average citation rate. Desloovere K was identified as the most productive author, while Graham HK received the highest number of citations. Keyword analysis revealed that “cerebral palsy,” “botulinum toxin,” and “spasticity” were central themes, while concepts such as “rehabilitation,” “gait analysis,” and “quality of life” also stood out. In recent years, the use of technological terms such as “ultrasound” and “electromyography” has increased. In addition, intraglandular BoNT‑A applications for the treatment of “sialorrhea” have been highlighted. The study also noted that BoNT‑A in the upper limb is recommended to be combined with rehabilitation in order to achieve functional gains. The literature emphasizes that data on long‑term efficacy remain limited and that there is a need for multicenter, prospective studies.
Source: OSMANGAZİ JOURNAL OF MEDICINE
DOI: 10.20515/otd.1748777
Authors: Gizem Sarıçimen, Ayşe Merve Aydoğan
Institution: Eskişehir City Hospital
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4413995070