Year: 2025
Type: article
Study design: Case Report
Abstract: Background Gordonia spp. is a rare infectious disease that has been reported in only 18 cases to date as a cause of peritoneal dialysis-related peritonitis. This is the first report of peritonitis associated with peritoneal dialysis caused by Gordonia otitidisand is a valuable case in which long-term intravenous vancomycin administration was successful. Case presentation A 48-year-old female. She started peritoneal dialysis at the age of 47 years due to end-stage renal failure caused by chronic glomerulonephritis. She was hospitalized for peritonitis three months after the start of dialysis. We administered cefazolin and ceftazidime intravenously and detected Gordonia otitidis in the drainage fluid after long-term culture for approximately 6 days. Therefore, we switched to vancomycin and treated the patient intravenously for a total of 6 weeks while checking blood levels and trough values in the drainage fluid. The patient had an increase in the number of draining cells for 3 weeks after the start of treatment, but the number of draining cells improved after that, and no relapse was observed 6 months after the end of treatment, suggesting that the treatment was successful. Conclusions When encountering peritoneal dialysis-associated peritonitis for the Gordonia genus, long-term intravenous administration of vancomycin should be considered as one of the treatments.
Source: Renal Replacement Therapy
Institution: SHOWA Medical University Koto Toyosu Hospital
Language: English
Subfield: Microbiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413998647