Year: 2024
Type: article
Study design: Case Report
Abstract: Palmoplantar keratoderma is a disease characterizedbyexcessive thickening of the epidermis in palms and soles.The diseasecan be hereditary or acquired at the early onset of the disease, and the involvement of many family members points to the congenital type. In addition, many congenital cases harbor additional phenotypic manifestations. Hereby, we report an 11-year-old male patient with early onset palmoplantar keratoderma associated with woolly hair. The combination of palmoplantar keratoderma and woolly hair is uncommon. It has been reported as part of the Naxos and the Carvajal syndrome, both caused by mutation in desmosomal proteins and sometimes cardiomyopathy, but not in our case.The patient experiencedprolonged remission of his symptoms with autologous bone marrow-derived mononuclear cell infusion. The current technique can be used as one treatment strategy in such cases.
DOI: 10.58564/jmob.17
Authors: Abdulmajeed alwan Hammadi, Jamal alrawi
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4414005965