Comparison of partial pressure of oxygen between compression-only CPR and standard CPR in simulated adult cardiac arrest - A manikin-based clinical modelling
Year: 2025
Type: article
Abstract: Background and Aims: Compression-only cardiopulmonary resuscitation (CPR) has been shown to be as effective as conventional CPR, and oxygen supplementation during compression-only CPR may be beneficial. The study aimed to compare the arterial oxygen levels achieved while supplementing oxygen through high flow nasal cannula (HFNC) during compression-only CPR and bag-mask ventilation (BMV) during conventional CPR in simulated cardiac arrest scenarios on a high-fidelity simulator. Methods: The study included a simulated cardiac arrest created on a human patient simulator (HPS). The simulation included two sets of scenarios. In Simulation A, cardiac arrest was simulated on HPS, and compression-only CPR was provided by AutoPulse, and oxygen supplementation was provided using HFNC. In Simulation B, chest compression was provided by AutoPulse, and BMV was supplemented with oxygen at 15 L/min at a compression-to-ventilation ratio of 30:2. Both simulation scenarios were evaluated for three different starting PaO 2 values: 100 mmHg, 80 mmHg, and 60 mmHg. The change in PaO 2 and PAO 2 values was recorded every minute for 6 minutes. Statistical analysis was conducted using SPSS Statistics (Version 24.0; IBM, Armonk, NY), and P < 0.05 was considered statistically significant. Results: In Simulation A, at a starting PaO 2 of 100 mmHg, there was an increase in the PaO 2 at the 2 nd minute, which was sustained till the 6 th minute. PaO 2 values were persistently higher at all time points as compared to Simulation B ( P < 0.001). At a starting PaO 2 of 80 mmHg, there was no change in PaO 2 in Simulation A as compared to a sustained fall in Simulation B ( P < 0.001). At the starting PaO 2 of 60 mmHg, a decrease in PaO 2 was observed in both Simulation A and Simulation B ( P = 0.57). Conclusion: In a simulated setting, compression-only CPR with HFNC results in better PaO 2 levels compared to conventional CPR with BMV.
Source: Indian Journal of Anaesthesia
Language: English
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414013168