Work

Qualitative assessment of rabies antibody in dogs pre and post vaccination in some communities in Plateau State

Year: 2025

Type: article

Abstract: This study aimed to conduct a qualitative assessment of rabies virus antibody among domesticated dogs in some communities in Plateau State, Nigeria. A total of 45 domesticated dogs from eight (8) communities within Jos South and East local government areas (LGAs) were sampled. Two serum samples were collected from each dog, 1 pre-vaccination and the other 2 weeks post-vaccination, totaling 90. A serological assay was performed using a commercial IgG (Dog) ELISA kit acquired from Demeditec® Diagnostics GmbH, Germany, for the determination of IgG antibodies against rabies virus in the samples. The results revealed that 36 (80 %) of the dogs were positive for rabies immunoglobulin G, and 9 (20 %) were negative in pre-vaccination assessment across the communities. It also revealed a significant increase in the positive rabies immunoglobulin G post-vaccination by 96 %. Of the 8 LGAs studied, the dogs in 7 of the LGAs (90%) showed a significant (p ≤ 0.05) increase in positive (≥ 0.34) rabies antibody titer. Only 1 LGA (10 %) showed a level of antibody titer below < 0.34, which was considered significant.

Source: Science World Journal

DOI: 10.4314/swj.v20i2.46

Authors: Nzenwata Emeka, Tekki Ishaya Sini, Meseko Clement Adebajo

Institutions: University of Ibadan, National Veterinary Research Institute, Kaduna State University

Language: English

Topic: Rabies epidemiology and control

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy, Institute for Life and Earth Sciences, Pan African University