Work

Intrapleural Steroid Therapy for Recurrent Malignant Pleural Effusion: A Case Report

Year: 2025

Type: article

Abstract: Malignant pleural effusion (MPE) is a common complication in advanced cancer, often causing significant dyspnea. We present a case of a 57-year-old woman with recurrent MPE who was managed with intrapleural triamcinolone acetate. The intervention delayed fluid reaccumulation by 15 days and improved her symptoms and functional status, with no adverse effects observed. The proposed mechanism involves VEGF inhibition and reduced vascular permeability. This case highlights intrapleural corticosteroids as a potential palliative option in managing recurrent MPE when conventional treatments are not suitable.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.70827

Authors: Shima Rani Sarker, Imtiaz Faruq, Jheelam Biswas

Institutions: Bangladesh Medical University, National Institute of Cancer Research and Hospital

Language: English

Topic: Pleural and Pulmonary Diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820