Work

Successful Treatment of Verrucous Epidermal Nevus With Full-Thickness Skin Excision: A Case Report and Literature Review

Year: 2025

Type: article

Abstract: Verrucous epidermal nevus (VEN) is a benign congenital hamartoma arising from abnormal keratinocyte proliferation, often presenting as linear, hyperpigmented, verrucous plaques along the lines of Blaschko, and it is usually a cause of major cosmetic concern. We present the case of an 18-year-old woman with a VEN on the medial aspect of her left arm, progressively enlarging since infancy. Examination revealed a 5 cm × 2 cm × 1 cm linear, hyperpigmented, verrucous plaque. A complete surgical excision with 3-mm margins was performed and histopathology confirmed the diagnosis of VEN. At two-month follow-up, the patient had complete wound healing, no recurrence, and satisfaction with the cosmetic result. This case highlights that complete surgical excision remains the gold standard for localized VEN, offering definitive cure and excellent long-term outcomes for appropriately selected patients, despite the risk of scarring.

Source: Cureus

DOI: 10.7759/cureus.91557

Authors: Ricardo Cid-Puente, Frida I Rosas-Lezama, Laura S De León-Puga, Amairani Tovar-Garcia, Julieta C Corral-Chavez

Institutions: Universidad Autónoma de Zacatecas "Francisco García Salinas", Mexican Social Security Institute, Pemex (Mexico), Secretaria de Salud

Language: English

Topic: Genetic and rare skin diseases.

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414037906